2r38: Difference between revisions

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==About this Structure==
==About this Structure==
2R38 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R38 OCA].  
2R38 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R38 OCA].  


==Reference==
==Reference==
Structural and Kinetic Analysis of Pyrrolidine-Based Inhibitors of the Drug-Resistant Ile84Val Mutant of HIV-1 Protease., Bottcher J, Blum A, Heine A, Diederich WE, Klebe G, J Mol Biol. 2008 Jul 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18692068 18692068]
<ref group="xtra">PMID:18692068</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Single protein]]
[[Category: Blum, A.]]
[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
[[Category: Boettcher, J.]]
[[Category: Diederich, W E.]]
[[Category: Heine, A.]]
[[Category: Klebe, G.]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Protein-ligand complex]]
[[Category: Protein-ligand complex]]


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Revision as of 09:58, 17 February 2009

File:2r38.png

Template:STRUCTURE 2r38

I84V HIV-1 protease mutant in complex with a carbamoyl decorated pyrrolidine-based inhibitor

Template:ABSTRACT PUBMED 18692068

About this Structure

2R38 is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  1. Bottcher J, Blum A, Heine A, Diederich WE, Klebe G. Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 protease. J Mol Biol. 2008 Nov 7;383(2):347-57. Epub 2008 Jul 29. PMID:18692068 doi:10.1016/j.jmb.2008.07.062

Page seeded by OCA on Tue Feb 17 11:58:12 2009

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