2r2m: Difference between revisions
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[[Image:2r2m. | [[Image:2r2m.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
2R2M is a | 2R2M is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2M OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:17889527</ref><references group="xtra"/> | |||
[[Category: Hirudo medicinalis]] | [[Category: Hirudo medicinalis]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
[[Category: Spurlino, J.]] | [[Category: Spurlino, J.]] | ||
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[[Category: Zymogen]] | [[Category: Zymogen]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:32:29 2009'' | ||
Revision as of 11:32, 17 February 2009
2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors
Template:ABSTRACT PUBMED 17889527
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
2R2M is a 3 chains structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T. 2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:17889527 doi:10.1016/j.bmcl.2007.09.013
Page seeded by OCA on Tue Feb 17 13:32:29 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Hirudo medicinalis
- Homo sapiens
- Thrombin
- Spurlino, J.
- Acute phase
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Kringle
- Polymorphism
- Protease
- Protease inhibitor
- Secreted
- Serine protease
- Serine protease inhibitor
- Sulfation
- Zymogen
