|
|
| Line 20: |
Line 20: |
|
| |
|
| ==About this Structure== | | ==About this Structure== |
| 1THZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1THZ OCA]. | | 1THZ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1THZ OCA]. |
|
| |
|
| ==Reference== | | ==Reference== |
| Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening., Xu L, Li C, Olson AJ, Wilson IA, J Biol Chem. 2004 Nov 26;279(48):50555-65. Epub 2004 Sep 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15355974 15355974]
| | <ref group="xtra">PMID:15355974</ref><ref group="xtra">PMID:12501179</ref><ref group="xtra">PMID:12974624</ref><ref group="xtra">PMID:14756553</ref><ref group="xtra">PMID:14966129</ref><references group="xtra"/> |
| | |
| Structural insights into the avian AICAR transformylase mechanism., Wolan DW, Greasley SE, Beardsley GP, Wilson IA, Biochemistry. 2002 Dec 31;41(52):15505-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12501179 12501179]
| |
| | |
| Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site., Wolan DW, Greasley SE, Wall MJ, Benkovic SJ, Wilson IA, Biochemistry. 2003 Sep 23;42(37):10904-14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12974624 12974624]
| |
| | |
| Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor., Wolan DW, Cheong CG, Greasley SE, Wilson IA, Biochemistry. 2004 Feb 10;43(5):1171-83. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14756553 14756553]
| |
| | |
| Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates., Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA, J Biol Chem. 2004 Apr 23;279(17):18034-45. Epub 2004 Feb 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14966129 14966129]
| |
| [[Category: Gallus gallus]] | | [[Category: Gallus gallus]] |
| [[Category: Single protein]]
| |
| [[Category: Li, C.]] | | [[Category: Li, C.]] |
| [[Category: Olson, A J.]] | | [[Category: Olson, A J.]] |
| Line 43: |
Line 34: |
| [[Category: Virtual ligand screening]] | | [[Category: Virtual ligand screening]] |
|
| |
|
| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 18:57:02 2008'' | | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:42:40 2009'' |
