2p4j: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 20: Line 20:


==About this Structure==
==About this Structure==
2P4J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4J OCA].  
2P4J is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4J OCA].  


==Reference==
==Reference==
Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands., Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni SS, Xu X, Chang W, Weerasena V, Turner R, Koelsch G, Bilcer G, Tang J, J Med Chem. 2007 May 17;50(10):2399-407. Epub 2007 Apr 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17432843 17432843]
<ref group="xtra">PMID:17432843</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Single protein]]
[[Category: Ghosh, A K.]]
[[Category: Ghosh, A K.]]
[[Category: Hong, L.]]
[[Category: Hong, L.]]
Line 40: Line 39:
[[Category: Structure based drug design]]
[[Category: Structure based drug design]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 19:25:56 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:06:40 2009''

Revision as of 12:06, 17 February 2009

File:2p4j.png

Template:STRUCTURE 2p4j

Crystal structure of beta-secretase bond to an inhibitor with Isophthalamide Derivatives at P2-P3

Template:ABSTRACT PUBMED 17432843

About this Structure

2P4J is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni SS, Xu X, Chang W, Weerasena V, Turner R, Koelsch G, Bilcer G, Tang J. Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands. J Med Chem. 2007 May 17;50(10):2399-407. Epub 2007 Apr 14. PMID:17432843 doi:10.1021/jm061338s

Page seeded by OCA on Tue Feb 17 14:06:40 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA