1e26: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
1E26 is a | 1E26 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E26 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:11052789</ref><references group="xtra"/> | |||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Pneumocystis carinii]] | [[Category: Pneumocystis carinii]] | ||
[[Category: Cody, V.]] | [[Category: Cody, V.]] | ||
[[Category: Galitsky, N.]] | [[Category: Galitsky, N.]] | ||
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[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:08:56 2009'' | ||
Revision as of 12:08, 17 February 2009
DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.
Template:ABSTRACT PUBMED 11052789
About this Structure
1E26 is a 1 chain structure of sequence from Pneumocystis carinii. Full crystallographic information is available from OCA.
Reference
- Gangjee A, Yu J, McGuire JJ, Cody V, Galitsky N, Kisliuk RL, Queener SF. Design, synthesis, and X-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent. J Med Chem. 2000 Oct 19;43(21):3837-51. PMID:11052789
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