2an3: Difference between revisions

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==About this Structure==
==About this Structure==
2AN3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN3 OCA].  
2AN3 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN3 OCA].  


==Reference==
==Reference==
Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis., Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL, Biochemistry. 2005 Dec 27;44(51):16875-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16363801 16363801]
<ref group="xtra">PMID:16363801</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phenylethanolamine N-methyltransferase]]
[[Category: Phenylethanolamine N-methyltransferase]]
[[Category: Single protein]]
[[Category: Gee, C L.]]
[[Category: Gee, C L.]]
[[Category: Grunewald, G L.]]
[[Category: Grunewald, G L.]]
Line 41: Line 40:
[[Category: Substrate structure]]
[[Category: Substrate structure]]


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Revision as of 15:00, 17 February 2009

File:2an3.png

Template:STRUCTURE 2an3

Structure of PNMT with S-adenosyl-L-homocysteine and the semi-rigid analogue acceptor substrate cis-(1R,2S)-2-amino-1-tetralol.

Template:ABSTRACT PUBMED 16363801

Disease

Known disease associated with this structure: Hypertension, essential, 145500 (1) OMIM:[171190]

About this Structure

2AN3 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis. Biochemistry. 2005 Dec 27;44(51):16875-85. PMID:16363801 doi:https://dx.doi.org/10.1021/bi051636b

Page seeded by OCA on Tue Feb 17 17:00:50 2009

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