2np8: Difference between revisions

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{{ABSTRACT_PUBMED_17157005}}
{{ABSTRACT_PUBMED_17157005}}
==Disease==
Known disease associated with this structure: Colon cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603072 603072]]


==About this Structure==
==About this Structure==
2NP8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NP8 OCA].  
2NP8 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NP8 OCA].  


==Reference==
==Reference==
Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors., Tari LW, Hoffman ID, Bensen DC, Hunter MJ, Nix J, Nelson KJ, McRee DE, Swanson RV, Bioorg Med Chem Lett. 2007 Feb 1;17(3):688-91. Epub 2006 Nov 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17157005 17157005]
<ref group="xtra">PMID:17157005</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Single protein]]
[[Category: Bensen, D C.]]
[[Category: Bensen, D C.]]
[[Category: Hoffman, I D.]]
[[Category: Hoffman, I D.]]
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[[Category: Kinase inhibitor]]
[[Category: Kinase inhibitor]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:48:53 2009''

Revision as of 15:48, 17 February 2009

File:2np8.png

Template:STRUCTURE 2np8

Structural Basis for the Inhibition of Aurora A Kinase by a Novel Class of High Affinity Disubstituted Pyrimidine Inhibitors

Template:ABSTRACT PUBMED 17157005

Disease

Known disease associated with this structure: Colon cancer, susceptibility to OMIM:[603072]

About this Structure

2NP8 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Tari LW, Hoffman ID, Bensen DC, Hunter MJ, Nix J, Nelson KJ, McRee DE, Swanson RV. Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors. Bioorg Med Chem Lett. 2007 Feb 1;17(3):688-91. Epub 2006 Nov 2. PMID:17157005 doi:https://dx.doi.org/10.1016/j.bmcl.2006.10.086

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