2oyh: Difference between revisions

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==About this Structure==
==About this Structure==
2OYH is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OYH OCA].  
2OYH is a 10 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OYH OCA].  


==Reference==
==Reference==
Probing the gamma2 calcium-binding site: studies with gammaD298,301A fibrinogen reveal changes in the gamma294-301 loop that alter the integrity of the "a" polymerization site., Kostelansky MS, Lounes KC, Ping LF, Dickerson SK, Gorkun OV, Lord ST, Biochemistry. 2007 May 1;46(17):5114-23. Epub 2007 Apr 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17411074 17411074]
<ref group="xtra">PMID:17411074</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Gorkun, O V.]]
[[Category: Gorkun, O V.]]
[[Category: Kostelansky, M S.]]
[[Category: Kostelansky, M S.]]
Line 38: Line 37:
[[Category: Variant fibrinogen]]
[[Category: Variant fibrinogen]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 01:07:43 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:57:08 2009''

Revision as of 15:57, 17 February 2009

File:2oyh.png

Template:STRUCTURE 2oyh

Crystal Structure of Fragment D of gammaD298,301A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-Amide

Template:ABSTRACT PUBMED 17411074

Disease

Known disease associated with this structure: Afibrinogenemia, congenital OMIM:[134820], Amyloidosis, hereditary renal OMIM:[134820], Dysfibrinogenemia, alpha type, causing bleeding diathesis OMIM:[134820], Dysfibrinogenemia, alpha type, causing recurrent thrombosis OMIM:[134820], Afibrinogenemia, congenital OMIM:[134830], Dysfibrinogenemia, beta type OMIM:[134830], Thrombophilia, dysfibrinogenemic OMIM:[134830], Dysfibrinogenemia, gamma type OMIM:[134850], Hypofibrinogenemia, gamma type OMIM:[134850], Thrombophilia, dysfibrinogenemic OMIM:[134850]

About this Structure

2OYH is a 10 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Kostelansky MS, Lounes KC, Ping LF, Dickerson SK, Gorkun OV, Lord ST. Probing the gamma2 calcium-binding site: studies with gammaD298,301A fibrinogen reveal changes in the gamma294-301 loop that alter the integrity of the "a" polymerization site. Biochemistry. 2007 May 1;46(17):5114-23. Epub 2007 Apr 6. PMID:17411074 doi:10.1021/bi602607a

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