3d20: Difference between revisions

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==About this Structure==
==About this Structure==
3D20 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D20 OCA].  
3D20 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D20 OCA].  


==Reference==
==Reference==
Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir., Liu F, Kovalevsky AY, Tie Y, Ghosh AK, Harrison RW, Weber IT, J Mol Biol. 2008 Aug 1;381(1):102-15. Epub 2008 Jul 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18597780 18597780]
<ref group="xtra">PMID:18597780</ref><ref group="xtra">PMID:16962136</ref><ref group="xtra">PMID:16277992</ref><references group="xtra"/>
 
Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114., Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT, J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16962136 16962136]
 
Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S., Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT, J Mol Biol. 2005 Dec 9;354(4):789-800. Epub 2005 Oct 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16277992 16277992]
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Single protein]]
[[Category: Ghosh, A K.]]
[[Category: Ghosh, A K.]]
[[Category: Harrison, R W.]]
[[Category: Harrison, R W.]]
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[[Category: Zinc-finger]]
[[Category: Zinc-finger]]


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