2op3: Difference between revisions

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==About this Structure==
==About this Structure==
2OP3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OP3 OCA].  
2OP3 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OP3 OCA].  


==Reference==
==Reference==
Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode., Inagaki H, Tsuruoka H, Hornsby M, Lesley SA, Spraggon G, Ellman JA, J Med Chem. 2007 May 31;50(11):2693-9. Epub 2007 May 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17469812 17469812]
<ref group="xtra">PMID:17469812</ref><references group="xtra"/>
[[Category: Cathepsin S]]
[[Category: Cathepsin S]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Ellman, J A.]]
[[Category: Ellman, J A.]]
[[Category: Hornsby, M.]]
[[Category: Hornsby, M.]]
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[[Category: Substrate activity screening]]
[[Category: Substrate activity screening]]


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Revision as of 16:57, 17 February 2009

File:2op3.png

Template:STRUCTURE 2op3

The structure of cathepsin S with a novel 2-arylphenoxyacetaldehyde inhibitor derived by the Substrate Activity Screening (SAS) method

Template:ABSTRACT PUBMED 17469812

About this Structure

2OP3 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Inagaki H, Tsuruoka H, Hornsby M, Lesley SA, Spraggon G, Ellman JA. Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode. J Med Chem. 2007 May 31;50(11):2693-9. Epub 2007 May 1. PMID:17469812 doi:https://dx.doi.org/10.1021/jm070111+

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