2gs2: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
2GS2 is a | 2GS2 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GS2 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:16777603</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Cole, P A.]] | [[Category: Cole, P A.]] | ||
[[Category: Gureasko, J.]] | [[Category: Gureasko, J.]] | ||
| Line 39: | Line 38: | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:55:07 2009'' | ||
Revision as of 18:55, 17 February 2009
Crystal Structure of the active EGFR kinase domain
Template:ABSTRACT PUBMED 16777603
Disease
Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]
About this Structure
2GS2 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Zhang X, Gureasko J, Shen K, Cole PA, Kuriyan J. An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell. 2006 Jun 16;125(6):1137-49. PMID:16777603 doi:10.1016/j.cell.2006.05.013
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