1xxd: Difference between revisions

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==About this Structure==
==About this Structure==
1XXD is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXD OCA].  
1XXD is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXD OCA].  


==Reference==
==Reference==
Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions., Jin L, Pandey P, Babine RE, Gorga JC, Seidl KJ, Gelfand E, Weaver DT, Abdel-Meguid SS, Strickler JE, J Biol Chem. 2005 Feb 11;280(6):4704-12. Epub 2004 Nov 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15545266 15545266]
<ref group="xtra">PMID:15545266</ref><references group="xtra"/>
[[Category: Coagulation factor XIa]]
[[Category: Coagulation factor XIa]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Abdel-Meguid, S S.]]
[[Category: Abdel-Meguid, S S.]]
[[Category: Babine, R E.]]
[[Category: Babine, R E.]]
Line 45: Line 44:
[[Category: Serine protein]]
[[Category: Serine protein]]


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Revision as of 22:26, 17 February 2009

File:1xxd.png

Template:STRUCTURE 1xxd

Crystal Structure of the FXIa Catalytic Domain in Complex with mutated Ecotin

Template:ABSTRACT PUBMED 15545266

Disease

Known disease associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[264900], Factor XI deficiency, autosomal recessive OMIM:[264900]

About this Structure

1XXD is a 4 chains structure of sequences from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Jin L, Pandey P, Babine RE, Gorga JC, Seidl KJ, Gelfand E, Weaver DT, Abdel-Meguid SS, Strickler JE. Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions. J Biol Chem. 2005 Feb 11;280(6):4704-12. Epub 2004 Nov 15. PMID:15545266 doi:10.1074/jbc.M411309200

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