2erj: Difference between revisions

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==Disease==
==Disease==
Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Diabetes mellitus, insulin-dependent, susceptibility to, 10 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Combined immunodeficiency, X-linked, moderate OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency, X-linked OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency due to IL2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147680 147680]]
Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Diabetes, mellitus, insulin-dependent, susceptibility to, 10 , OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Combined immunodeficiency, X-linked, moderate OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency, X-linked OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency due to IL2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147680 147680]]


==About this Structure==
==About this Structure==
2ERJ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERJ OCA].  
2ERJ is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERJ OCA].  


==Reference==
==Reference==
Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor., Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA, Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2788-93. Epub 2006 Feb 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16477002 16477002]
<ref group="xtra">PMID:16477002</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Debler, E W.]]
[[Category: Debler, E W.]]
[[Category: Stauber, D J.]]
[[Category: Stauber, D J.]]
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[[Category: Interleukin-2 gamma receptor]]
[[Category: Interleukin-2 gamma receptor]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:00:57 2009''

Revision as of 04:01, 18 February 2009

File:2erj.png

Template:STRUCTURE 2erj

Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2

Template:ABSTRACT PUBMED 16477002

Disease

Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[147730], Diabetes, mellitus, insulin-dependent, susceptibility to, 10 , OMIM:[147730], Combined immunodeficiency, X-linked, moderate OMIM:[308380], Severe combined immunodeficiency, X-linked OMIM:[308380], Severe combined immunodeficiency due to IL2 deficiency OMIM:[147680]

About this Structure

2ERJ is a 8 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA. Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2788-93. Epub 2006 Feb 13. PMID:16477002

Page seeded by OCA on Wed Feb 18 06:00:57 2009

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