1oyt: Difference between revisions

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==About this Structure==
==About this Structure==
1OYT is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OYT OCA].  
1OYT is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OYT OCA].  


==Reference==
==Reference==
A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions., Olsen JA, Banner DW, Seiler P, Obst Sander U, D'Arcy A, Stihle M, Muller K, Diederich F, Angew Chem Int Ed Engl. 2003 Jun 6;42(22):2507-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12800172 12800172]
<ref group="xtra">PMID:12800172</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Thrombin]]
[[Category: Thrombin]]
[[Category: Banner, D W.]]
[[Category: Banner, D W.]]
[[Category: Olsen, J A.]]
[[Category: Olsen, J A.]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:28:13 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:14:08 2009''

Revision as of 07:14, 18 February 2009

File:1oyt.png

Template:STRUCTURE 1oyt

COMPLEX OF RECOMBINANT HUMAN THROMBIN WITH A DESIGNED FLUORINATED INHIBITOR

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

1OYT is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Olsen JA, Banner DW, Seiler P, Obst Sander U, D'Arcy A, Stihle M, Muller K, Diederich F. A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions. Angew Chem Int Ed Engl. 2003 Jun 6;42(22):2507-11. PMID:12800172 doi:10.1002/anie.200351268

Page seeded by OCA on Wed Feb 18 09:14:08 2009

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