Sandbox4: Difference between revisions

Revision as of 21:16, 2 March 2009

This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!'

Jamal Salah and Vishwa Shah. We are doing deoxyhemoglobin.

Ligands:

HEM, NBN, SO4

Structural annotation:
Resources:	CATH : 101M000 UniProt : P02185

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

@@ Line 5: / Line 5: @@
 {{STRUCTURE_101m |  PDB=101m  |  SCENE=  }}
-Deoxyhemoglobin is the form of hemoglobin without oxygen bound.  Hemoglobin is an assembly of four globular protein subunits. Each protein chain configures into alpha-helix structural segments connected together in a folded arrangement, containing a hole or pocket which binds the heme group. A heme group composes of an iron ion held in a heterocyclic ring called a porphyrin. The iron ion coordinates with the four nitrogens in the center of the ring. The iron is also bound to the globular protein through the imidazole ring of the F8 histidine residue, below the porphyrin ring. (1)
-) <themedicalbiochemistrypage.org/hemoglobin-myoglobin.html>