Sandbox21: Difference between revisions
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'''This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks! | '''This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks! | ||
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by Kevin Chen 3-3-09 | by Kevin Chen 3-3-09 | ||
==Trypsin== | |||
Trypsin is an enzyme that breaks down protein, that is produced in the pancreas and then secreted in to the small intestines. It is a homolog of chymotrypsin and it works by cleaving at the peptide bond after residues with long, positively charged side chains. An aspartate residue which attracts and stabilizes a positively charged arginine or lysine residue in the substrate. The disease of cystic fibrosis is the result of deficiency in transport of trypsin and other digestive enzymes from the pancreas. | Trypsin is an enzyme that breaks down protein, that is produced in the pancreas and then secreted in to the small intestines. It is a homolog of chymotrypsin and it works by cleaving at the peptide bond after residues with long, positively charged side chains. An aspartate residue which attracts and stabilizes a positively charged arginine or lysine residue in the substrate. The disease of cystic fibrosis is the result of deficiency in transport of trypsin and other digestive enzymes from the pancreas. | ||
==Structure== | ==Structure== | ||