Sandbox13: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
Student (talk | contribs)
students
33,923 edits
No edit summary
Student (talk | contribs)
students
33,923 edits
Line 10: Line 10:


==About this Structure==
==About this Structure==
This is the protein Human Serum Albumin(HSA),it has <scene name='Sandbox13/Alpha_helices/1'>alpha helices</scene> (shown in red) and also <scene name='Sandbox13/Beta_sheets/1'>beta sheets</scene> (shown in blue), now the <scene name='Sandbox13/Hydrophobic/1'>hydrophobic</scene> parts of HSA are on both the surface and inside. HSA is an abundant transport protein found in plasma that binds a wide variety of drugs in two primary binding sites (I and II) and can have a significant impact on their pharmacokinetics.
This is the Human Serum Albumin(HSA),it has <scene name='Sandbox13/Alpha_helices/1'>alpha helices</scene> (shown in red), <scene name='Sandbox13/Beta_sheets/1'>beta sheets</scene> (shown in blue), and the <scene name='Sandbox13/Hydrophobic/1'>hydrophobic</scene> parts. HSA is an abundant transport protein found in plasma that binds a wide variety of drugs in two primary binding sites (I and II) and can have a significant impact on their pharmacokinetics.


Reference: Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I.,Petitpas, I., Bhattacharya, A.A., Twine, S., East, M., Curry, S., VJ.Biol.Chem. v276 pp. 22804-9, 2001
Reference: Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I.,Petitpas, I., Bhattacharya, A.A., Twine, S., East, M., Curry, S., VJ.Biol.Chem. v276 pp. 22804-9, 2001
Retrieved from "https://proteopedia.org/Sandbox13"