User:Nathan Roy: Difference between revisions
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Once Gag is localized to discreet sites on the plasma membrane, multimerization of Gag takes place quite quickly , driven by the CA domain, and more specifically our focus here, the C-terminal domain of CA (CTD). There are four helices that contribute to the interaction of CA CTD with it's partner. A side-by-side interaction has been proposed | Once Gag is localized to discreet sites on the plasma membrane, multimerization of Gag takes place quite quickly , driven by the CA domain, and more specifically our focus here, the C-terminal domain of CA (CTD). There are four helices that contribute to the interaction of CA CTD with it's partner. A side-by-side interaction has been proposed (Figure 2), but many believe the forces involved in the side-by-side model are not great enough to account for the organization and structural stability of assembled Gag.<applet load='1aum' size='200' frame='true' align='right' caption='FIGURE 3. Side-by-side structure of CA CTD' /> | ||