User:Adam Meade/Sandbox 1: Difference between revisions
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Since there are bacteria that have to have iron level-mediating proteins present but do not have the Fur (ferric uptake regulator) protein, there must be another protein that takes its place. In the case of ''B. japonicum'', which does not have the Fur protein, the Irr protein was found to be the regulator of iron levels within the cell.<ref>2) Small, S. K., S. Puri, and M. R. O’Brian. 2009. <u>Heme-dependent metalloregulation by the iron response regulator (Irr) protein in Rhizobium and other alpha-proteobacteria</u>. Biometals 22:89-97.</ref> | Since there are bacteria that have to have iron level-mediating proteins present but do not have the Fur (ferric uptake regulator) protein, there must be another protein that takes its place. In the case of ''B. japonicum'', which does not have the Fur protein, the Irr protein was found to be the regulator of iron levels within the cell.<ref>2) Small, S. K., S. Puri, and M. R. O’Brian. 2009. <u>Heme-dependent metalloregulation by the iron response regulator (Irr) protein in Rhizobium and other alpha-proteobacteria</u>. Biometals 22:89-97.</ref> | ||
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'''Structure of the Proposed Irr Protein'''<applet load='Irr.pdb' size='300' color='black' frame='true' align='right' caption='3D Image of proposed Irr protein'/> | |||
The amino acid sequence used to derive the structure shown is as follows: | |||
1 msentaphhd ddvhaaalls grqpaltgcp whdvnemlqs aglrptrqrm algwllfgkg | |||
61 arhltaemly eeatlakvpv slatvyntln qltdagllrq vsvdgtktyf dtnvtthhhy | |||
121 ylenshelvd iedphlalsk mpevpegyei aridmvvrlr kkr | |||
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==References== | ==References== | ||
