Factor IX: Difference between revisions

Revision as of 17:25, 26 April 2009 view source Nadia Dorochko (talk \| contribs) 420 edits No edit summary ← Older edit		Revision as of 17:26, 26 April 2009 view source Nadia Dorochko (talk \| contribs) 420 edits No edit summary Newer edit →
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	Carboxyglutamate: Post-translational carboxylation of glutamate residues (Glu) into gammacarboxy glutamate (Gla) ==		Carboxyglutamate: Post-translational carboxylation of glutamate residues (Glu) into gammacarboxy glutamate (Gla) ==

	The post-translational modification of the glutamic acid residues of the FIX polypeptide is carried out by vitamin K-dependent -glutamyl carboxylase (1). Vitamin K-dependent carboxylase is a membrane associated protein in the endoplasmic reticulum. It converts a multiple of glutamic acid residues which are located within 40 residues of a propeptide-containing sequence into -[http://www.molecular-haemostasis.de/grfx/pix carboxyglutamate] (2).		The post-translational modification of the glutamic acid residues of the FIX polypeptide is carried out by vitamin K-dependent -glutamyl carboxylase (1). Vitamin K-dependent carboxylase is a membrane associated protein in the endoplasmic reticulum. It converts a multiple of glutamic acid residues which are located within 40 residues of a propeptide-containing sequence into -[http://www.molecular-haemostasis.de/grfx/pix/research_02_big.jpg carboxyglutamate] (2).

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