Factor IX: Difference between revisions
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{{STRUCTURE_1pfx| PDB=1pfx | SCENE= }} | {{STRUCTURE_1pfx| PDB=1pfx | SCENE= }} | ||
<span style="color:Brown">'''<scene name='Factor_IX/Ixstructure/3'>Factor IX</scene>'''</span> (plasma thromboplastin component, Christmas factor, or hemophilia B factor) is a 57-kDa vitamin K-dependent procoagulant glycoprotein. It is synthesized by the liver hepatocyte as a [[pre-prozymogen]] that requires extensive posttranslational modification. The [[pre-prozymogen]] contains a pre-peptide (hydrophobic signal peptide) at its amino terminal that transports the growing polypeptide into the lumen of the Endoplasmic Reticulum. Once inside the ER, this signal peptide is cleaved by a signal peptidase. | <span style="color:Brown">'''<scene name='Factor_IX/Ixstructure/3'>Factor IX</scene>'''</span> (plasma thromboplastin component, Christmas factor, or hemophilia B factor) is a 57-kDa vitamin K-dependent procoagulant glycoprotein. It is synthesized by the liver hepatocyte as a [[pre-prozymogen]] that requires extensive posttranslational modification. The [[pre-prozymogen]] contains a pre-peptide (hydrophobic signal peptide) at its amino terminal that transports the growing polypeptide into the lumen of the Endoplasmic Reticulum. Once inside the ER, this signal peptide is cleaved by a signal peptidase. | ||
