1fkn: Difference between revisions

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{{STRUCTURE_1fkn|  PDB=1fkn  |  SCENE=  }}  
{{STRUCTURE_1fkn|  PDB=1fkn  |  SCENE=  }}  


===STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR===
===Structure of Beta-Secretase Complexed with Inhibitor===




Line 26: Line 26:
[[Category: Amyloid-beta Precursor Protein]]
[[Category: Amyloid-beta Precursor Protein]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Ghosh, A.]]
[[Category: Ghosh, A.]]
[[Category: Hong, L.]]
[[Category: Hong, L.]]
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[[Category: Base]]
[[Category: Base]]
[[Category: Beta-secretase]]
[[Category: Beta-secretase]]
[[Category: Hydrolase/hydrolase inhibitor complex]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:59:11 2009''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May  6 09:11:53 2009''

Revision as of 06:11, 6 May 2009

File:1fkn.png


Drag the structure with the mouse to rotate
1fkn, resolution 1.90Å (default scene)
Non-Standard Residues: 1OL
Activity: Memapsin 2, with EC number 3.4.23.46
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Structure of Beta-Secretase Complexed with Inhibitor

Template:ABSTRACT PUBMED 11021803

About this Structure

1FKN is a 4 chains structure of sequences from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. Full crystallographic information is available from OCA.

Reference

  1. Hong L, Koelsch G, Lin X, Wu S, Terzyan S, Ghosh AK, Zhang XC, Tang J. Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor. Science. 2000 Oct 6;290(5489):150-3. PMID:11021803

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