Epitopes: Difference between revisions
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An epitope is the portion of the surface of an antigen that binds to an [[Antibody|antibody]], or the peptide fragment of a protein antigen that binds to the T lymphocyte antigen receptor when presented by the cognate major histocompatibility protein. The best way to identify an antibody epitope is from a [[X-Ray Crystallography|crystal structure] of the antibody:antigen complex, where the contacts are evident. There are several [[#Epitope Prediction Servers|servers that attempt to predict epitopes]]. | An epitope is the portion of the surface of an antigen that binds to an [[Antibody|antibody]], or the peptide fragment of a protein antigen that binds to the T lymphocyte antigen receptor when presented by the cognate major histocompatibility protein. The best way to identify an antibody epitope is from a [[X-Ray Crystallography|crystal structure]] of the antibody:antigen complex, where the contacts are evident. There are several [[#Epitope Prediction Servers|servers that attempt to predict epitopes]]. | ||
==Terminology== | ==Terminology== | ||