Nitric Oxide Synthase: Difference between revisions
From Proteopedia
Jump to navigationJump to search
| Line 30: | Line 30: | ||
{{STRUCTURE_2g6h|PDB=2g6h|SCENE=Nitric_oxide_synthase/Nos_oxygenase_med_cofaktore/1}} | {{STRUCTURE_2g6h|PDB=2g6h|SCENE=Nitric_oxide_synthase/Nos_oxygenase_med_cofaktore/1}} | ||
The <scene name='Sandbox_5/Nos_oxygenase_med_cofaktore/3'>oxygenase domain</scene> contains the active site of the enzyme. The active site binds the substrate L | The <scene name='Sandbox_5/Nos_oxygenase_med_cofaktore/3'>oxygenase domain</scene> contains the active site of the enzyme. The active site binds the substrate L<scene name='Nitric_oxide_synthase/Nos_oxygenase_arg/1'>Arginine</scene> ([http://en.wikipedia.org/wiki/Arginine Arginine]) which is converted into citruline and NO (explained in details below). The domain has three cofactors bound: | ||
<scene name='Nitric_oxide_synthase/Nos_oxygenase_bh4/1'>H4B</scene> ([http://en.wikipedia.org/wiki/BH4 (6R).5,6,7,8-Tetrahydrobiopterin]) | <scene name='Nitric_oxide_synthase/Nos_oxygenase_bh4/1'>H4B</scene> ([http://en.wikipedia.org/wiki/BH4 (6R).5,6,7,8-Tetrahydrobiopterin]) | ||