3fj6: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3fj6.jpg|left|200px]]


The entry 3fj6 is ON HOLD until Paper Publication
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{{STRUCTURE_3fj6|  PDB=3fj6  |  SCENE=  }}


Authors: Davies, M., Heikkila, T.J., McConkey, G.A., Fishwick, C.W.G., Parsons, M.R., Johnson, A.P.
===Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2===


Description: Human dihydroorotate dehydrogenase complexed with a leflunomide derivative


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan  7 09:35:10 2009''
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==About this Structure==
3FJ6 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FJ6 OCA].
 
==Reference==
<ref group="xtra">PMID:19351152</ref><references group="xtra"/>
[[Category: Dihydroorotate oxidase]]
[[Category: Homo sapiens]]
[[Category: Heikkila, T.]]
[[Category: Alpha-beta barrel tim barrel]]
[[Category: Fad]]
[[Category: Flavoprotein]]
[[Category: Membrane]]
[[Category: Mitochondrion]]
[[Category: Mitochondrion inner membrane]]
[[Category: Oxidoreductase]]
[[Category: Polymorphism]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Transit peptide]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 18:02:20 2009''

Revision as of 15:02, 10 June 2009

File:3fj6.jpg

Template:STRUCTURE 3fj6

Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2

Template:ABSTRACT PUBMED 19351152

About this Structure

3FJ6 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Davies M, Heikkila T, McConkey GA, Fishwick CW, Parsons MR, Johnson AP. Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases. J Med Chem. 2009 May 14;52(9):2683-93. PMID:19351152 doi:10.1021/jm800963t

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