2wf0: Difference between revisions
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Revision as of 17:29, 24 June 2009
HUMAN BACE-1 IN COMPLEX WITH 4-ETHYL-N-((1S,2R)-2-HYDROXY-1-(PHENYLMETHYL)-3-(((3-(TRIFLUOROMETHYL)PHENYL)METHYL)AMINO) PROPYL)-8-(2-OXO-1-PYRROLIDINYL)-6-QUINOLINECARBOXAMIDE
Template:ABSTRACT PUBMED 19428244
About this Structure
2WF0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Charrier N, Clarke B, Cutler L, Demont E, Dingwall C, Dunsdon R, Hawkins J, Howes C, Hubbard J, Hussain I, Maile G, Matico R, Mosley J, Naylor A, O'Brien A, Redshaw S, Rowland P, Soleil V, Smith KJ, Sweitzer S, Theobald P, Vesey D, Walter DS, Wayne G. Second generation of BACE-1 inhibitors. Part 1: The need for improved pharmacokinetics. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3664-8. Epub 2009 Apr 17. PMID:19428244 doi:10.1016/j.bmcl.2009.03.165
Page seeded by OCA on Wed Jun 24 20:33:43 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Brien, A O.
- Charrier, N.
- Clarke, B.
- Cutler, L.
- Demont, E.
- Dingwall, C.
- Dunsdon, R.
- Hawkins, J.
- Howes, C.
- Hubbard, J.
- Hussain, I.
- Maile, G.
- Matico, R.
- Mosley, J.
- Naylor, A.
- Redshaw, S.
- Rowland, P.
- Smith, K J.
- Soleil, V.
- Sweitzer, S.
- Theobald, P.
- Vesey, D.
- Walter, D S.
- Wayne, G.
- Alternative splicing
- Asp-2
- Aspartyl protease
- Bace-1
- Beta-secretase
- Beta-site app cleaving enzyme
- Disulfide bond
- Glycoprotein
- Hydrolase
- Memapsin-2
- Membrane
- Polymorphism
- Protease
- Transmembrane
- Zymogen
