3h5b: Difference between revisions

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{{Seed}}
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[[Image:3h5b.jpg|left|200px]]
[[Image:3h5b.png|left|200px]]


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[[Category: Wild type protease]]
[[Category: Wild type protease]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 17 10:09:14 2009''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 25 08:22:59 2009''

Revision as of 05:23, 25 June 2009

File:3h5b.png

Template:STRUCTURE 3h5b

Crystal structure of wild type HIV-1 protease with novel P1'-ligand GRL-02031

Template:ABSTRACT PUBMED 19473017

About this Structure

3H5B is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

Reference

  1. Ghosh AK, Leshchenko-Yashchuk S, Anderson DD, Baldridge A, Noetzel M, Miller HB, Tie Y, Wang YF, Koh Y, Weber IT, Mitsuya H. Design of HIV-1 Protease Inhibitors with Pyrrolidinones and Oxazolidinones as Novel P1'-Ligands To Enhance Backbone-Binding Interactions with Protease: Synthesis, Biological Evaluation, and Protein-Ligand X-ray Studies (infinity). J Med Chem. 2009 May 27. PMID:19473017 doi:10.1021/jm900303m

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