3e2t: Difference between revisions
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The substrate specificity of TPH1 has been studied previously. These studies have shown that the substrate specificity i mainly controlled by Tyr236 and Phe314. Tyr236 is also involved in the binding of the tetrahydrobiopterin as seen in the structure of human TPH1 ([[1mlw]]). | <br/> | ||
The substrate specificity of TPH1 has been studied previously. These studies have shown that the substrate specificity i mainly controlled by Tyr236 <ref>PMID: 10993738</ref> and Phe314<ref>PMID: 11747434</ref> <ref>PMID: 11922614</ref>. Tyr236 is also involved in the binding of the tetrahydrobiopterin as seen in the structure of human TPH1 ([[1mlw]]). | |||
