1htn: Difference between revisions
New page: left|200px<br /> <applet load="1htn" size="450" color="white" frame="true" align="right" spinBox="true" caption="1htn, resolution 2.8Å" /> '''HUMAN TETRANECTIN, A... |
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==About this Structure== | ==About this Structure== | ||
1HTN is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1HTN OCA]]. | 1HTN is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Sites: CA1 and CA2. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1HTN OCA]]. | ||
==Reference== | ==Reference== | ||
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[[Category: tetranectin]] | [[Category: tetranectin]] | ||
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Revision as of 06:23, 30 October 2007
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HUMAN TETRANECTIN, A TRIMERIC PLASMINOGEN BINDING PROTEIN WITH AN ALPHA-HELICAL COILED COIL
Overview
Tetranectin is a plasminogen kringle 4-binding protein. The crystal, structure has been determined at 2.8 A resolution using molecular, replacement. Human tetranectin is a homotrimer forming a triple, alpha-helical coiled coil. Each monomer consists of a carbohydrate, recognition domain (CRD) connected to a long alpha-helix. Tetranectin has, been classified in a distinct group of the C-type lectin superfamily but, has structural similarity to the proteins in the group of collectins., Tetranectin has three intramolecular disulfide bridges. Two of these are, conserved in the C-type lectin superfamily, whereas the third is present, only in long-form CRDs. Tetranectin represents the first structure of a, long-form CRD with intact calcium-binding sites. In tetranectin, the third, disulfide ... [(full description)]
About this Structure
1HTN is a [Single protein] structure of sequence from [Homo sapiens] with CA as [ligand]. Structure known Active Sites: CA1 and CA2. Full crystallographic information is available from [OCA].
Reference
Crystal structure of tetranectin, a trimeric plasminogen-binding protein with an alpha-helical coiled coil., Nielsen BB, Kastrup JS, Rasmussen H, Holtet TL, Graversen JH, Etzerodt M, Thogersen HC, Larsen IK, FEBS Lett. 1997 Jul 28;412(2):388-96. PMID:9256258
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