3gep: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3gep.jpg|left|200px]]


The entry 3gep is ON HOLD until Paper Publication
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{{STRUCTURE_3gep|  PDB=3gep  |  SCENE=  }}


Authors: Guddat, L.W., Keough, D.T., de Jersey, J.
===Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine===


Description: Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun  4 07:17:38 2009''
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{{ABSTRACT_PUBMED_19527031}}
 
==About this Structure==
3GEP is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEP OCA].
 
==Reference==
<ref group="xtra">PMID:19527031</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Hypoxanthine phosphoribosyltransferase]]
[[Category: Guddat, L W.]]
[[Category: Jersey, J.]]
[[Category: Keough, D T.]]
[[Category: Acetylation]]
[[Category: Acyclic nucleoside phosphonate]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Glycosyltransferase]]
[[Category: Gout]]
[[Category: Magnesium]]
[[Category: Malarial chemotherapeutic]]
[[Category: Metal-binding]]
[[Category: Phosphoribosyltransferase]]
[[Category: Purine salvage]]
[[Category: Purine salvage pathway]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 13:07:14 2009''

Revision as of 10:07, 19 August 2009

File:3gep.jpg

Template:STRUCTURE 3gep

Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine

Template:ABSTRACT PUBMED 19527031

About this Structure

3GEP is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Keough DT, Hockova D, Holy A, Naesens LM, Skinner-Adams TS, Jersey J, Guddat LW. Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics. J Med Chem. 2009 Jul 23;52(14):4391-9. PMID:19527031 doi:10.1021/jm900267n

Page seeded by OCA on Wed Aug 19 13:07:14 2009

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