1gwl: Difference between revisions
New page: left|200px<br /> <applet load="1gwl" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gwl, resolution 1.51Å" /> '''CARBOHYDRATE BINDIN... |
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==About this Structure== | ==About this Structure== | ||
1GWL is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Piromyces_equi Piromyces equi]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GWL OCA]]. | 1GWL is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Piromyces_equi Piromyces equi]]. Structure known Active Site: BM1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GWL OCA]]. | ||
==Reference== | ==Reference== | ||
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[[Category: mannohexaose]] | [[Category: mannohexaose]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:33:43 2007'' | ||
Revision as of 06:29, 30 October 2007
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CARBOHYDRATE BINDING MODULE FAMILY29 COMPLEXED WITH MANNOHEXAOSE
Overview
Carbohydrate-protein recognition is central to many biological processes., Enzymes that act on polysaccharide substrates frequently contain, noncatalytic domains, "carbohydrate-binding modules" (CBMs), that target, the enzyme to the appropriate substrate. CBMs that recognize specific, plant structural polysaccharides are often able to accommodate both the, variable backbone and the side-chain decorations of heterogeneous ligands., "CBM29" modules, derived from a noncatalytic component of the Piromyces, equi cellulase/hemicellulase complex, provide an example of this selective, yet flexible recognition. They discriminate strongly against some, polysaccharides while remaining relatively promiscuous toward both, beta-1,4-linked manno- and cello-oligosaccharides. This feature may, reflect ... [(full description)]
About this Structure
1GWL is a [Single protein] structure of sequence from [Piromyces equi]. Structure known Active Site: BM1. Full crystallographic information is available from [OCA].
Reference
Promiscuity in ligand-binding: The three-dimensional structure of a Piromyces carbohydrate-binding module, CBM29-2, in complex with cello- and mannohexaose., Charnock SJ, Bolam DN, Nurizzo D, Szabo L, McKie VA, Gilbert HJ, Davies GJ, Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14077-82. Epub 2002 Oct 21. PMID:12391332
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