3hk3: Difference between revisions

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{{Seed}}
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[[Image:3hk3.jpg|left|200px]]
[[Image:3hk3.png|left|200px]]


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===Crystal structure of murine thrombin mutant W215A/E217A (one molecule in the asymmetric unit)===
===Crystal structure of murine thrombin mutant W215A/E217A (one molecule in the asymmetric unit)===


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{{ABSTRACT_PUBMED_19586901}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:15252033</ref><references group="xtra"/>
<ref group="xtra">PMID:19586901</ref><ref group="xtra">PMID:15252033</ref><references group="xtra"/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Zymogen]]
[[Category: Zymogen]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  8 12:44:32 2009''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 08:35:19 2009''

Revision as of 05:35, 16 September 2009

File:3hk3.png

Template:STRUCTURE 3hk3

Crystal structure of murine thrombin mutant W215A/E217A (one molecule in the asymmetric unit)

Template:ABSTRACT PUBMED 19586901

About this Structure

3HK3 is a 2 chains structure of sequences from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Gandhi PS, Page MJ, Chen Z, Bush-Pelc L, Di Cera E. Mechanism of the anticoagulant activity of thrombin mutant W215A/E217A. J Biol Chem. 2009 Sep 4;284(36):24098-105. Epub 2009 Jul 8. PMID:19586901 doi:10.1074/jbc.M109.025403
  2. Pineda AO, Chen ZW, Caccia S, Cantwell AM, Savvides SN, Waksman G, Mathews FS, Di Cera E. The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket. J Biol Chem. 2004 Sep 17;279(38):39824-8. Epub 2004 Jul 13. PMID:15252033 doi:https://dx.doi.org/10.1074/jbc.M407272200

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