2eb3 | pdb_00002eb3
From Proteopedia
Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP
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| 2eb3, resolution 2.84Å | |||||||||||||
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| Sites: | AC1 | ||||||||||||
| Ligands: | ANP | ||||||||||||
| Gene: | EGFR (Homo sapiens) | ||||||||||||
| Activity: | Receptor protein-tyrosine kinase, with EC number 2.7.10.1 | ||||||||||||
| Related: | 2EB2, 2ZGE, 2ZGF
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Disease
Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]
About this Structure
2EB3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 02:46:23 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Single protein
- Kukimoto-Niino, M.
- RSGI, RIKEN Structural Genomics/Proteomics Initiative.
- Senba, K.
- Shirouzu, M.
- Yamamoto, T.
- Yokoyama, S.
- Yoshikawa, S.
- Atp-binding
- Cell cycle
- Disease mutation
- Ec 2 7.10 1
- Kinase
- National project on protein structural and functional analyse
- Nppsfa
- Phosphorylation
- Receptor
- Riken structural genomics/proteomics initiative
- Rsgi
- Structural genomic
- Transferase
- Transmembrane
- Tyrosine-protein kinase
