2b7a | pdb_00002b7a
From Proteopedia
The structural basis of Janus Kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor
Disease
Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[147796], Myelofibrosis, idiopathic OMIM:[147796], Myeloproliferative disorder with erythrocytosis OMIM:[147796], Polycythemia vera OMIM:[147796], Thrombocythemia, essential OMIM:[147796], Budd-Chiari syndrome OMIM:[147796]
About this Structure
2B7A is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lucet IS, Fantino E, Styles M, Bamert R, Patel O, Broughton SE, Walter M, Burns CJ, Treutlein H, Wilks AF, Rossjohn J. The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor. Blood. 2006 Jan 1;107(1):176-83. Epub 2005 Sep 20. PMID:16174768 doi:https://dx.doi.org/10.1182/blood-2005-06-2413
Page seeded by OCA on Tue Feb 17 12:52:11 2009
