4dl4 | pdb_00004dl4
From Proteopedia
Human DNA polymerase eta inserting dCMPNPP opposite the 3'G of cisplatin crosslinked Gs (Pt-GG1).
About this Structure
4dl4 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zhao Y, Biertumpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang W. Structural basis of human DNA polymerase eta-mediated chemoresistance to cisplatin. Proc Natl Acad Sci U S A. 2012 Apr 23. PMID:22529383 doi:10.1073/pnas.1202681109
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- DNA-directed DNA polymerase
- Homo sapiens
- Biertumpfel, Christian
- Gregory, Mark
- Hanaoka, Fumio
- Hua, Yue-Jin
- Yang, Wei
- Zhao, Ye
- Chemoresistence
- Cisplatin
- Dna distorsion
- Human dna polymerse eta
- Inhibition
- Kinetic
- Molecular splint
- Nucleotidyl transfer reaction
- Pcna
- Second tls polymerase
- Transferase-dna-inhibitor complex
- Translesion synthesis
