1vec

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Template:STRUCTURE 1vec

Crystal structure of the N-terminal domain of rck/p54, a human DEAD-box protein

Template:ABSTRACT PUBMED 16611246

Disease

[DDX6_HUMAN] Note=A chromosomal aberration involving DDX6 may be a cause of hematopoietic tumors such as B-cell lymphomas. Translocation t(11;14)(q23;q32).

Function

[DDX6_HUMAN] In the process of mRNA degradation, may play a role in mRNA decapping.

About this Structure

1vec is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Matsui T, Hogetsu K, Usukura J, Sato T, Kumasaka T, Akao Y, Tanaka N. Structural insight of human DEAD-box protein rck/p54 into its substrate recognition with conformational changes. Genes Cells. 2006 Apr;11(4):439-52. PMID:16611246 doi:10.1111/j.1365-2443.2006.00951.x

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