3n59 | pdb_00003n59
From Proteopedia
Type II dehydroquinase from Mycobacterium Tuberculosis complexed with 3-dehydroshikimate
Template:ABSTRACT PUBMED 21410435
Function
[AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
About this Structure
3n59 is a 24 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Dias MV, Snee WC, Bromfield KM, Payne R, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem J. 2011 Mar 17. PMID:21410435 doi:10.1042/BJ20110002
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- 3-dehydroquinate dehydratase
- Mycobacterium tuberculosis
- Abell, C.
- Blundell, T L.
- Bromfield, K M.
- Ciulli, A.
- Dias, M V.B.
- Howard, N I.
- Palaninathan, S K.
- Payne, R.
- Sacchettini, J C.
- Snee, W C.
- TBSGC, TB Structural Genomics Consortium.
- 3-dehydroshikimate
- Aromatic amino acid biosynthesis
- Dehydratase
- Drug target
- Lyase
- Shikimate pathway
- Structural genomic
- Tb structural genomics consortium
- Tbsgc
- Tuberculosis
