5ipp | pdb_00005ipp
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Structure of Bacillus NanoRNase A active site mutant bound to a mononucleotide
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Structural highlights
FunctionNRNA_BACSU Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for 3-mers. Directionality is controversial; shown to degrade 5-mers and less in a 3' to 5' direction (PubMed:17586819), and 11-mers in a 5' to 3' direction (PubMed:21087930). Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP.[1] [2] [3] See AlsoReferences
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This page was last modified 12:35, 6 March 2024.