8gun | pdb_00008gun
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Crystal structure of mutant H528A of EsaD from Staphylococcus aureus
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Structural highlights
FunctionESSD_STAA8 Component of the type VII secretion system (Ess). Plays a role in Ess secretion during infection. Required for the efficient secretion of EsxA. Required for abscess formation and staphylococcal persistence in host tissues (By similarity). Possesses a toxic DNase activity that is modulated by EssG by forming a nuclease toxin-antitoxin pair. This nuclease toxin targets competitor bacteria (PubMed:27723728).[UniProtKB:A0A0H2XIV9][1] References
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This page was last modified 07:27, 3 April 2024.