9hvf | pdb_00009hvf

Native human PPP1R15B-P-eIF2-eIF2B complex

spinqualitylabelsall models 9hvf, resolution 3.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9hvf is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.8Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease EI2BG_HUMAN Juvenile or adult CACH syndrome;Congenital or early infantile CACH syndrome;Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry. Function EI2BG_HUMAN Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

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