9vm2

Structure of DOCK6-Cdc42 complex protomer

spinqualitylabelsall models 9vm2, resolution 3.94Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9vm2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.94Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease DOCK6_HUMAN Adams-Oliver syndrome. The disease is caused by variants affecting the gene represented in this entry. Function DOCK6_HUMAN Acts as a guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Through its activation of CDC42 and RAC1, may regulate neurite outgrowth (By similarity).

Proteopedia Page Contributors and Editors (what is this?)

OCA