9x1f | pdb_00009x1f

NMR structure of the membrane-active toxin U11-MYRTX-Tb1a from ant Tetramorium bicarinatum in DPC micelle

spinqualitylabelsall models 9x1f Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9x1f is a 1 chain structure with sequence from Tetramorium bicarinatum. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR, 20 models Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TX11A_TETBN Neurotoxin that causes irreversible rapid flaccid paralysis in blowflies and honeybees upon intrathoracic injection (PubMed:37888631). Causes a quick and irreversible cytolytic effect (at 10 uM) indicating it possibly acts as a pore-forming peptide (PubMed:38786948). Shows only weak effect on aphids (A.pisum) at high doses 24 hours post intrathoracic injection (PubMed:37888631). In vitro, is not cytotoxic on the dipteran S2 Drosophila embryonic cell line (PubMed:37888631).

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