3iit | pdb_00003iit
From Proteopedia
Factor XA in complex with a cis-1,2-diaminocyclohexane derivative
About this Structure
3iit is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yoshikawa K, Kobayashi S, Nakamoto Y, Haginoya N, Komoriya S, Yoshino T, Nagata T, Mochizuki A, Watanabe K, Suzuki M, Kanno H, Ohta T. Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties. Bioorg Med Chem. 2009 Dec 15;17(24):8221-33. Epub 2009 Oct 17. PMID:19900814 doi:10.1016/j.bmc.2009.10.024
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor Xa
- Homo sapiens
- Suzuki, M.
- Blood coagulation
- Blood coagulation factor
- Calcium-binding
- Cleavage on pair of basic residue
- Disulfide bond
- Egf-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Plasma
- Protease
- Protein inhibitor complex
- Secreted
- Serine protease
- Zymogen
