1o0d | pdb_00001o0d

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Template:STRUCTURE 1o0d

File:1o0d.png

Human Thrombin complexed with a d-Phe-Pro-Arg-type Inhibitor and a C-terminal Hirudin derived exo-site inhibitor

Template:ABSTRACT PUBMED 12781189

About this Structure

1o0d is a 3 chain structure of Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Lange UE, Baucke D, Hornberger W, Mack H, Seitz W, Hoffken HW. D-Phe-Pro-Arg type thrombin inhibitors: unexpected selectivity by modification of the P1 moiety. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2029-33. PMID:12781189

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