2b7a | pdb_00002b7a

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Template:STRUCTURE 2b7a

File:2b7a.png

The structural basis of Janus Kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor

Template:ABSTRACT PUBMED 16174768

About this Structure

2b7a is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Lucet IS, Fantino E, Styles M, Bamert R, Patel O, Broughton SE, Walter M, Burns CJ, Treutlein H, Wilks AF, Rossjohn J. The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor. Blood. 2006 Jan 1;107(1):176-83. Epub 2005 Sep 20. PMID:16174768 doi:https://dx.doi.org/10.1182/blood-2005-06-2413

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