2g0n | pdb_00002g0n
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The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
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Structural highlights
FunctionRAC3_HUMAN Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles.[1] Evolutionary ConservationCheck, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences | ||||||||||||||||||||
This page was last modified 09:34, 30 August 2023.