3bgx | pdb_00003bgx

E. coli Thymidylate Synthase C146S mutant complexed with dTMP and MTF

spinqualitylabelsall models 3bgx, resolution 1.93Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3bgx is a 1 chain structure with sequence from "bacillus_coli"_migula_1895 "bacillus coli" migula 1895. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: MEF, SO4, TMP NonStd Res: CXM Related: 3b9h, 3bfi, 3bhl, 3bhr Gene: thyA ("Bacillus coli" Migula 1895) Activity: Thymidylate synthase, with EC number 2.1.1.45 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [TYSY_ECOLI] Provides the sole de novo source of dTMP for DNA biosynthesis. This protein also binds to its mRNA thus repressing its own translation. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Thymidylate synthase 3D structures

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