3e3u | pdb_00003e3u
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Crystal structure of Mycobacterium tuberculosis peptide deformylase in complex with inhibitor
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Structural highlights
FunctionDEF_MYCTU Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity). Evolutionary ConservationCheck, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. | ||||||||||||||||||||
This page was last modified 09:44, 21 February 2024.