5t2q | pdb_00005t2q
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Unliganded Human HVEM at 1.9A in P 1 21 1
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Structural highlights
FunctionTNR14_HUMAN Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.[1] See AlsoReferences | ||||||||||||||||||
This page was last modified 15:35, 6 March 2024.