6csd

V308E mutant of cytochrome P450 2D6 complexed with prinomastat

spinqualitylabelsall models 6csd, resolution 2.39Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6csd is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.391Å Ligands: CPS, HEM, PN0, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CP2D6_HUMAN Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. See Also Cytochrome P450 3D structures

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